DW and I drove from NYC to near Wilmington, NC last month.  We went via the DelMarVa Peninsula and even thereafter stayed off the major highways.  
According to the GPS, I drove through a lot of cornfields.  It was pretty clear it either did not know where we were or did not know where the road was on numerous occasions, and I suspect the later in most cases.  
It's a tool.  Only a tool.  It needs to be checked against other tools, if you really have no clue as to wehre you are.  other tools would include maps and your own common sense.