"...Drug runners have to have some great tricks, right..."

Indeed they do. But most of them are wanting to transport fairly small packages ('cept for MJ), and they don't worry about ready access, or access without tools. Many hidden compartments behind the dash, requiring the entire dash to be removed to get at the stash. Or the frame/gas tank cut open, the load put inside, then welded shut. Not much help here...

Valuables out of sight, stuff like water in plain view (so no one breaks into to see what is in the big box)