Aspirin works for me for headaches, also it is recommended for reduced chance of heart attacks. And I did have one a few months ago and am now taking them every day.
I also have and take Percocet for several broken bones and damaged knees & shoulder from a motorcycle accident. But I never take more then the prescription says to. My prescription says I can take 2 if needed, But I have found that if I take one with 2 aspirin it does just as well as taking 2 of the Percocet. And it doesn’t put me to sleep.
I have a relative that is on Vicodin and he gave me well over 100 of them, but I have never taken one of them. I never did any research on them and am very reluctant to just take something I know nothing about.
I think the issue is to not take any medication excessively, or to mix & match without a doctors recommendation.
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You can run, but you'll only die tired.