I consider the Gulf Coast to be one of the safest areas to be for the following reasons and with the following exceptions:

Good:
1) Great area irt Nuclear Conflict-will receive lttle fallout and few targets within the region.
2) Irt weather-subject to severe weather including a few tornadoes (known areas), like most places, but we can see a hurricane coming from a week away. Occasional flooding can be a problem but pick your hacienda with care.
3) Geologically-very little activity (occasional 1's) that are cushioned/absorbed by the water/earth ratio.
4) Manmade problems-nuclear power plants-pick your hacienda with care. The same is true irt to transportation routes and junctions, just like anywhere else.
5) Plentiful food supply locally, year 'round.

Bad:
1) Coastal erosion and rising sea levels-My present home will be beach front property in 50 years.

Notes:
1) Hurricanes landing in my area lose at least 1 category of strength before they get to my home.