I was surprised to read once that a significant percentage--more than half in that particular survey--of unintentional overdoses were from combination drugs of Vicodin and Percocet which also contain acetominophen. People in chronic pain often develop resistance to the narcotics, so they increase the dosage, not realizing or not being that concerned that they're also upping the acetominophen dosage, too. I guess we're all brainwashed with TV ads that make us think that acetominophen is so safe.

I don't know the exact number, but tens of thousands ER visits are attributed to acetominophen overdoses each year.