In regards to reduction of mortality (reduce the chance of dieing), only aspirin and beta-blockers have been shown to be effective. O2, NTG, and morphine relieve symptoms but don’t reduce mortality. From a practical standpoint only ambulances would have prehospital access to O2 and morphine.
In regards to reduction of mortality MUCH more then ASA and beta blockers have been shown to be effective. Nitro and Morphine along with Aspirin and Oxygen has been shown to improve short term mortality and while not the definitive care for a MI they are the like aggressive bleeding control in a GSW patient... they will get you to the definitive care.
I don't know where you level of knowledge, training or experience is but your post reads as a paraphrasal or Wikipedia
There is certainly still some risk of an unknown allergy or unexpected interaction. Some number of people likely to have a heart attack are already on aspirin and/or other blood thinners that could make them very prone to bleeding. So stuffing aspirin into people you happen to think are having a heart attack isn't something you want to do casually. Every therapy and drug has side effects. Don't go off half-cocked.
Another good point and one I meant to make but missed. What medications we carry as laypersons should (in most cases) be kept for use on us and or families. Someone asks you for an Aspirin, fine but otherwise keep you treatments (and giving someone a drug or any kind, OTC or otherwise is a treatment) to within you scope of practice.
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