Having lived in the US for 18 yrs I can say that there is definitely a culture shock. Mostly subtle things but those noted above are true. With the internet it is a bit easier to hear about things from Canada.

There are two big issues taxation and medical. I strongly suggest you seek the advise of a COMPETENT tax expert (Canada-US-Canada issues) as part of your planning BEFORE making a final decision. Medical costs are also a significant issue. Not a big deal if you don't get sick or have chronic care needs. Income taxes are generally lower in the US but in my experience you pay it in other ways, medical costs, miscellaneous user fees, etc. Your situation may be different.

It also depends on whether you are thinking of moving down here temporarily but keeping a large number of expenses in Canada. With the current exchange rate it isn't a good as it once was.