Actually, the only information I've seen relavent to Quikclot or the like is on this situation. I was shown a video where they severed the femoral artery of an anethesized pig. They let it bleed for a few moments to get a really good flow going then dumped Quikclot into the wound and applied pressure. After several minutes of pressure they rinsed away the excess Quikclot and low and behold the wound had stopped bleeding. I was impressived by the performance.

I don't know if I like the idea of using the stuff if I don't have to, but the same is true of a tourniquet. For dire situations, this is something I'd want on hand (although I don't have any currently). Also, while the mixture of Quikclot and water may have heated up substancially, I don't think it was 300-400 degrees, keep in mind water boils at 212 F. MRE heaters get hot enough you can barely hold the corners, but you can still pretty well eat the meal inside right after you take it out. The stuffs meant for life threatening injures. Given the choice between losing a limb to a tourniquet or bleeding out, I'd rather lose a limb. Given the choice between being scalded and bleeding out, I'll take the scald.