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Using high-volt Li-Ion batteries require special care, so here are some rules/warnings:
-Do not overdischarge/overcharge
-Recharge drained batteries ASAP
-Do not short circuit
-Do not dispose of in fire
-Do not expose to extreme heat or water
-Only charge when you can be there watching
-REPEAT: NEVER CHARGE LI-ION CELLS UNATTENDED


Using LiFePo4 cells are safer, but with less capacity, but have double the number of charge cycles. The Nitecore D2 and D4 chargers will also charge LiFePo4 as well as Lithium Ion.

Lithium Ion and polymer technology are used widely, the same advice should also be applied to keeping an eye on your smart phone and Laptop as well. If using Lithium Ion cells such as 18650 and RCR123A ensure that they are protected cells.

Any cell that is short circuited presents a risk. It could be argued that a protected lithium cells may even be safer than even Alkaline or NiMh.

Be careful of the source and the quality of the Lithium Cells and ensure that they have protection circuits.