With target shooting, plinking and hunting in mind, I'd go with a .22 LR bolt action rifle. Back when I had one of the Savage .22LR/.410 combo guns, I never used the .410.

If it was going to be used exclusively for hunting I might go with the combo gun, then again, depending on the game available, I might not. For serious wingshooting, a 12 ga or 20 ga is more practical, I've just never seen the need of a .410 for small game or the usefulness for larger game. YMMV

OTOH a bolt action or semi-auto .22LR rifle can take a wide variety of small game and they give you a follow-on shot. With the over/under combo guns your follow-up shot is not another .22LR round.

There are a lot of good .22 LR rifles available from many manufacturers. With combo guns you have a much more limited selection.