I agree with most posters - I like it for a few select layers, but after that I'm pretty synthetic. I love SmarWool socks. I'd love an nice alpaca sweater. Suits made of wool seem nicer than those of cotton or canvas.

But in a rainstorm or blizzard, I'll take my synthetics, even if they do encase down. Sleeping in dry wool is nice, just make sure to ziploc those items.