I probably would not use OC in my house.

1) I may have to move. I can't do that nearly as well if the hallway is full of OC. I don't own a gas mask.

2) If I can't immediately find my wife and children and make sure they're safe, I'm going to move towards the intruder and be ready to neutralize any threat. OC spray isn't usually the best choice for this.

3) OC spray isn't as effective as firearms are in trained hands. In a home invasion, I'm not beholden to a police officer's continuum of force, I'm not trying to deter a low-grade threat, and I'm not in a non-permissive environment. There is no reason for me to not use the most effective tools at my disposal.