Don't think so... Celox works the same way as Quikclot w/o heat but than again new Quikclot has been improved so it is not a concern. Another great product is HemCon bandages, also no heat but quite expensive.
"Gen 1" Quikclot was a problem (minor burns around edge of the wound). "Gen 2" Quikclot was used in the study I read and used to answer your question and produced very low heat 45 C. We also use "gen 2" product. I guess formula had to be revised in order to compete with Celox. I would love to see some folow up studies on use of both products and outcome for patients.