I have two Mystery Ranch systems, they are quite posibly the greatest packs I have ever had!
Both packs are great, especially very heavy loads over rough terrain! I love the setup. Both packs have hundreds of hiking hours on them with nothing more than normal wear! They have been replaced by other, task specific, packs for SAR and Medical work but they are still my first choice for extended trips or when I need to carry huge loads!
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"Trust in God --and press-check. You cannot ignore danger and call it faith." -Duke